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Pittcon Announces ACS-DAC Co-programming 26 Aug 2008: Pittcon is pleased to announce the third year of co-programming with the ACS Division of Analytical Chemistry (ACS-DAC) with 12 sessions for Pittcon 2009, March 8-13, 2009, McCormick Place South, Chicago, IL. The Pittsburgh Conference
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Reaction optimization by parallel kinetic studies with the POLARstar Omega
22 Aug 2008: The yields of chemical reactions may vary considerably with parameters such as solvent, catalyst, temperature and reaction time. This application note monitors the metallation of a porphyrin with zinc as a function of solvent. Monitoring is ideally suited to the BMG LABTECH POLARstar Omega microplate reader due to its ability to acquire a full UV-visible absorbance spectrum of each well in less than one second. BMG LABTECH
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Thermo Fisher Scientific Bolsters Proteome Dynamics Offering with HUPO Product Launches
18 Aug 2008: Thermo Fisher Scientific Inc., the world leader in serving science, will introduce a new proteomics workflow solution at HUPO 2008, plus major upgrades to two premier Thermo Scientific software packages. Thermo Fisher Scientific
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Bruker Daltonics Showcasing Novel Proteomics Solutions Based on Mass Spectrometry at the 7th HUPO World Congress 2008 18 Aug 2008: Bruker Daltonics today is showcasing several new high performance mass spectrometry products and applications for proteomics at the 7th HUPO World Congress 2008. Bruker Daltonics Inc
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Agilent Technologies launches the world's most sensitive LC/MS/MS
01 Aug 2008: At ACS 2008, Agilent Technologies Inc. will present the latest in LC/MS/MS technology, breaking the femtogram sensitivity barrier. The new 6460 Triple Quadrupole LC/MS delivers best-in-class sensitivity in a wide range of applications, thanks to proprietary Agilent Jet Stream thermal gradient focusing technology. This is a breakthrough system that lowers detection limits six-fold relative to previous instruments to allow sub-femtogram detection levels for many compounds. Agilent Technologies
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Strategies for Automated Chromatographic Method Development
30 Jul 2008: Automated chromatographic method development has recently become a topic of considerable interest to the analytical chemistry world. The design of effective chromatographic methods is a complex task involving often conflicting goals. This paper will present new strategies for chromatographic method development that leverage modern method development tools, resulting in increases in method development efficiency. Advanced Chemistry Development, Inc., (ACD/Labs)
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High Performance Peptide Mapping Using Varian Capillary LC Columns 30 Jul 2008: Proteomics studies have played more and more important roles in drug development and biomarker discovery. Proteins in a sample are separated and identified by liquid chromatography-mass spectrometry (LC-MS). For protein-based biomarkers, the use of multidimensional LC coupled with MS and MS-MS is becoming a standard technology. This application note describes the how Varian capillary LC columns can be used for LC-MS separation of a tryptic digest of Bovine Serum Albumin (BSA). Varian Inc
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Analysis of Quetiapine and Vardenafil in Bovine Plasma by Omix® Pipette Tips for Micro Extraction 30 Jul 2008: Omix Pipette Tips for Micro Extraction are specially designed for small sample and elution volumes. Tips with 10 and 100 μL capacities are manufactured with 0.9 and 2.4 mg beds, respectively, of monolithic sorbent that minimizes dead volumes. Omix Pipette Tips are an ideal choice for extracting analytes from small samples, for example rat or mice plasma. This application describes a method using Omix C18 100 μL tips and LC/MS/MS to extract and analyze Vardenafil and Quetiapine from bovine plasma Varian Inc
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Thermo Fisher Scientific Exhibits LC-MS/MS Solution at AACC 29 Jul 2008: Thermo Fisher Scientific Inc., the world leader in serving science, today announced the success of its liquid chromatography tandem mass spectrometry (LC-MS/MS) solution at Ameritox. The Thermo Scientific TSQ Quantum Access™ triple quadrupole mass spectrometer, combined with the Thermo Scientific Aria™ TLX-4 system, uses TurboFlow™ and multiplexing technologies to offer the most advanced, most sensitive analytical method for clinical labs and is exhibited for the first time at AACC. Thermo Fisher Scientific
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